Skip To Main Content

Search

For optimal search results, please limit to 2 product keywords

If you are searching for information related to a product:

  • For optimal results, please enter at least 2 search terms in addition to product name
  • Example: [product name] [search term] [search term]
  • Example: Product + clinical trials
  • For an exact match, please include search terms in double quotations. For example: "Elevatum"

Ranibizumab (The Port Delivery System)

Modality: Recombinant humanized monoclonal antibody fragment

Disease State: Diabetes-Related Macular Edema (DME) and Neovascular age-related Macular Degeneration (nAMD)

Summary

Ranibizumab is designed to bind to and inhibit VEGF (vascular endothelial growth factor), a protein that is believed to play a critical role in the formation of new blood vessels (angiogenesis) and the hyperpermeability (leakiness) of the vessels.1

Clinical Trials

nAMD
Phase Enrollment Status Title
Phase III Enrolling A Phase IIIb, Global, Multicenter, Randomized, Visual Assessor-Masked Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System with Ranibizumab in Patients with Neovascular Age-Related Macular Degeneration View Details
Phase IV Enrolling A Phase IV, Multicenter, Open-Label Study to Assess Corneal Endothelial Cells in Patients with Neovascular Age-Related Macular Degeneration Treated with the Port Delivery System with Ranibizumab View Details
  1. Roche. Product Development Portfolio. January 30, 2025. Accessed February 12, 2025. https://www.roche.com/​solutions/​pipeline

Looking for more information?

Reach out to a Genentech Medical Science Liaison near you, or connect with the contact center.

Call the Trial Information Support Team: 1-888-662-6728 Hours: Monday-Friday, 5am-5pm PT

  • DME
    diabetic macular edema