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Explore the investigational molecules and recruiting clinical trials in our pipeline.
The clinical trials and molecule information included represent only a subset of the Roche/Genentech pipeline, specifically highlighting a selection of investigational molecules involved in actively recruiting Phase 3 trials. For a comprehensive overview of our full development portfolio or all actively recruiting Phase 3 trials, please visit genentech-clinicaltrials.com.
Recruiting Trials
Explore select clinical trials that are actively recruiting participants. To view all clinical trials related to a molecule, go to the section below.
Phase III: Afimkibart in UC (AMETRINE-1)
A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With afimkibart (RO7790121) in Patients With Moderately to Severely Active Ulcerative Colitis
Phase III: Afimkibart in UC (AMETRINE-2)
A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With afimkibart (RO7790121) in Patients With Moderately to Severely Active Ulcerative Colitis
Phase III: Afimkibart in CD (SIBERITE-1)
A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With afimkibart (RO7790121) in Patients With Moderately to Severely Active Crohn's Disease
Phase III: Afimkibart in CD (SIBERITE-2)
A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With afimkibart (RO7790121) in Patients With Moderately to Severely Active Crohn's Disease
Molecules
Explore our investigational molecules by phase. View individual molecules to explore all clinical trials related to that molecule.
These compounds and their uses are investigational and have not been approved by the U.S. Food and Drug Administration. This information is presented only for purposes of providing a general overview of clinical trials and should not be construed as a recommendation for use of any product for unapproved uses.
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Call the Trial Information Support Team: 1-888-662-6728 Hours: Monday-Friday, 5am-5pm PT