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Clinical Trials

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Actively Recruiting Trials

Explore clinical trials that are actively recruiting participants. To view all of our trials, go to clinicaltrials.gov

Immunology

Phase III: Afimkibart in UC (AMETRINE-1)

A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With afimkibart (R07790121) in Patients With Moderately to Severely Active Ulcerative Colitis

Immunology

Phase III: Afimkibart in UC (AMETRINE-2)

A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With afimkibart (R07790121) in Patients With Moderately to Severely Active Ulcerative Colitis

Immunology

Phase III: Afimkibart in CD (SIBERITE-1)

A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With afimkibart (R07790121) in Patients With Moderately to Severely Active Crohn's Disease

Immunology

Phase III: Afimkibart in CD (SIBERITE-2)

A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With afimkibart (R07790121) in Patients With Moderately to Severely Active Crohn's Disease

Oncology

Phase II: Atezolizumab in HCC (KIRROS)

A Phase II, Open-Label, Multi-Cohort, Multicenter Study in Patients With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis

Oncology

Phase III: Divarasib in Metastatic NSCLC (KRASCENDO 1)

A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Patients With Previously Treated KRAS G12C-Positive Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Oncology

Phase III: Giredestrant in BC (pionERA Breast Cancer (BC))

A Phase III Randomized, Open-Label Study Evaluating Efficacy and Safety of Giredestrant Compared With Fulvestrant, Both Combined With a CDK4/6 Inhibitor, in Patients With Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer With Resistance to Prior Adjuvant Endocrine Therapy

Oncology

Phase III: Glofitamab in 1L LBCL (SKYGLO)

A Phase III, Multicenter, Randomized, Open-Label Study Comparing the Efficacy and Safety of Glofitamab (RO7082859) in Combination With Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma

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