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Pipeline & Clinical Trials

Explore the investigational molecules and recruiting clinical trials in our pipeline.

The clinical trials and molecule information included represent only a subset of the Roche/Genentech pipeline, specifically highlighting a selection of investigational molecules involved in actively recruiting Phase 3 trials. For a comprehensive overview of our full development portfolio or all actively recruiting Phase 3 trials, please visit genentech-clinicaltrials.com.

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Recruiting Trials

Explore select clinical trials that are actively recruiting participants. To view all clinical trials related to a molecule, go to the section below.

Phase II: Fenebrutinib in Pediatric Relapsing Multiple Sclerosis (FENerations1)

An Open-label, Single-arm Study to Evaluate Pharmacokinetics, Pharmacodynamic Effects, Safety and Tolerability of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis

Phase III: Trontinemab in Alzheimer’s Disease (TRONTIER 1)

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (MCI to Mild Dementia Due to AD)

Phase III: Trontinemab in Alzheimer’s Disease (TRONTIER 2)

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (MCI to Mild Dementia Due to AD)

Screening study for Alzheimer's Disease (TRAVELLER)

Master Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies as Assessed by Biomarker Status and Cognition

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Molecules

Explore our investigational molecules by phase. View individual molecules to explore all clinical trials related to that molecule.

Molecule Disease State Modality
Fenebrutinib Multiple Sclerosis (MS) Bruton’s tyrosine kinase inhibitor (BTKi) View Molecule

View Clinical Trials

Trontinemab Alzheimer’s disease (AD) Brainshuttle™ bispecific 2+1 amyloid-beta targeting monoclonal antibody View Molecule

View Clinical Trials

These compounds and their uses are investigational and have not been approved by the U.S. Food and Drug Administration. This information is presented only for purposes of providing a general overview of clinical trials and should not be construed as a recommendation for use of any product for unapproved uses.

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Call the Trial Information Support Team: 1-888-662-6728 Hours: Monday-Friday, 5am-5pm PT